Influenza a Neuraminidase-Based Bivalent mRNA Vaccine Induces Th1-Type Immune Response and Provides Protective Effects in Mice

Influenza a Neuraminidase-Based Bivalent mRNA Vaccine Induces Th1-Type Immune Response and Provides Protective Effects in Mice

Vaccines are one of the most effective means of preventing influenza A, typically containing the hemagglutinin (HA) of the influenza A virus. However, antigenic drift and shift of the influenza A virus can lead to instability in vaccine efficacy. Compared to HA, the antigenic variation rate of neura...

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Bibliographic Details
Main Authors: Mingyang Li, Mengyuan Liu, Shaohui Song, Ruirui Zhao, Yun Xie, Jing Liu, Lilan Xu, Xuefeng Ma, Mingyu Song, Jian Zhou, Guoyang Liao
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Vaccines
Subjects:
mRNA vaccine
influenza A
neuraminidase
Th1
Online Access:https://www.mdpi.com/2076-393X/12/3/300

Internet

https://www.mdpi.com/2076-393X/12/3/300

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