Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis

Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis

PR domain-containing 1 with zinc finger domain (PRDM1) has been reported as a promoter of inflammation, which is a critical process involved in the pathogenesis of acute gouty arthritis. Herein, we sought to ascertain the function of PRDM1 in the development of acute gouty arthritis and related mech...

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Bibliographic Details
Main Authors: Qingsong Zhao, Nan Xia, Jinmei Xu, Yingnan Wang, Luwen Feng, Dihan Su, Zhifeng Cheng
Format: Article
Language:English
Published: Karger Publishers 2023-06-01
Series:Journal of Innate Immunity
Subjects:
inflammatory cytokines
macrophages
pyrin domain-containing 3
nlr family
acetylated α-tubulin
sirtuin 2
pr domain-containing 1 with zinc finger domain
acute gouty arthritis
Online Access:https://beta.karger.com/Article/FullText/530966

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