Deficiency of Splicing Factor 1 (SF1) Reduces Intestinal Polyp Incidence in <i>Apc<sup>Min/</sup></i><sup>+</sup> Mice

Background: Splicing factor 1 (SF1) is a conserved alternative splicing factor expressed in many different mammalian cell types. The genetically modified <i>Sf1+/−</i> (or <i>Sf1<sup>β-geo/+</sup></i>) mice express reduced levels of SF1 protein in mouse tissues, i...

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Bibliographic Details
Main Authors: Jyotsna D. Godavarthi, Shahrazad Polk, Lisa Nunez, Amruthesh Shivachar, Nancy L. Glenn Griesinger, Angabin Matin
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/11/398