Development of Diclofenac Sodium 3D Printed Cylindrical and Tubular-Shaped Tablets through Hot Melt Extrusion and Fused Deposition Modelling Techniques

Development of Diclofenac Sodium 3D Printed Cylindrical and Tubular-Shaped Tablets through Hot Melt Extrusion and Fused Deposition Modelling Techniques

The present study aimed to develop 3D printed dosage forms, using custom-made filaments loaded with diclofenac sodium (DS). The printed tablets were developed by implementing a quality by design (QbD) approach. Filaments with adequate FDM 3D printing characteristics were produced via hot melt extrus...

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Bibliographic Details
Main Authors: Tryfon Digkas, Alina Porfire, Jeroen Van Renterghem, Aseel Samaro, Gheorghe Borodi, Chris Vervaet, Andrea Gabriela Crișan, Sonia Iurian, Thomas De Beer, Ioan Tomuta
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceuticals
Subjects:
three-dimensional printing (3DP)
hot melt extrusion (HME)
quality by design (QbD)
release kinetics
Online Access:https://www.mdpi.com/1424-8247/16/8/1062

Internet

https://www.mdpi.com/1424-8247/16/8/1062

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