Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps

Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps

Introduction: The Adverse Outcome Pathway (AOP) concept facilitates rapid hazard assessment for human health risks. AOPs are constantly evolving, their number is growing, and they are referenced in the AOP-Wiki database, which is supported by the OECD. Here, we present a study that aims at identifyi...

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Main Authors: Thomas Jaylet, Thibaut Coustillet, Nicola M. Smith, Barbara Viviani, Birgitte Lindeman, Lucia Vergauwen, Oddvar Myhre, Nurettin Yarar, Johanna M. Gostner, Pablo Monfort-Lanzas, Florence Jornod, Henrik Holbech, Xavier Coumoul, Dimosthenis A. Sarigiannis, Philipp Antczak, Anna Bal-Price, Ellen Fritsche, Eliska Kuchovska, Antonios K. Stratidakis, Robert Barouki, Min Ji Kim, Olivier Taboureau, Marcin W. Wojewodzic, Dries Knapen, Karine Audouze
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Toxicology
Subjects:
adverse outcome pathway
AOP network
immunotoxicity
neurotoxicity
nongenotoxic carcinogenesis
diseases
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2024.1285768/full

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https://www.frontiersin.org/articles/10.3389/ftox.2024.1285768/full

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