Saffron offers hepatoprotection via up-regulation of hepatic farnesoid-X-activated receptors in a rat model of acetaminophen-induced hepatotoxicity
Objectives: The most important toxicity of acetaminophen is hepatotoxicity. Farnesoid X-activated receptors (FXR) are one of the nuclear receptor superfamily members which have a pivotal role in the bile acid regulation. The objective of the present study was to examine the role of FXR in mediating...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2021-11-01
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Series: | Avicenna Journal of Phytomedicine |
Subjects: | |
Online Access: | https://ajp.mums.ac.ir/article_18227_a040a3498c9370831602f25abe1dd88b.pdf |