Neutropenia and Large Granular Lymphocyte Leukemia: From Pathogenesis to Therapeutic Options

Large granular lymphocyte leukemia (LGLL) is a rare lymphoproliferative disorder characterized by the clonal expansion of cytotoxic T-LGL or NK cells. Chronic isolated neutropenia represents the clinical hallmark of the disease, being present in up to 80% of cases. New advances were made in the biol...

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Bibliographic Details
Main Authors: Giulia Calabretto, Antonella Teramo, Gregorio Barilà, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Gianpietro Semenzato, Renato Zambello
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/10/2800