Deubiquitylation machinery is required for embryonic polarity in Caenorhabditis elegans.

The Caenorhabditis elegans one-cell embryo polarizes in response to a cue from the paternally donated centrosome and asymmetrically segregates cell fate determinants that direct the developmental program of the worm. We have found that genes encoding putative deubiquitylating enzymes (DUBs) are requ...

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Bibliographic Details
Main Authors: Richard J McCloskey, Kenneth J Kemphues
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3510043?pdf=render