Discovery of a novel hybrid coumarin-hydroxamate conjugate targeting the HDAC1-Sp1-FOSL2 signaling axis for breast cancer therapy

Abstract Background Breast cancer is one of the most lethal cancers in women. Despite significant advances in the diagnosis and treatment of breast cancer, many patients still succumb to this disease, and thus, novel effective treatments are urgently needed. Natural product coumarin has been broadly...

詳細記述

書誌詳細
主要な著者: Sujie Zhu, Wenjing Zhu, Kaihua Zhao, Jie Yu, Wenxia Lu, Rui Zhou, Shule Fan, Weikaixin Kong, Feifei Yang, Peipei Shan
フォーマット: 論文
言語:English
出版事項: BMC 2024-07-01
シリーズ:Cell Communication and Signaling
主題:
オンライン・アクセス:https://doi.org/10.1186/s12964-024-01733-4