Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma

Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma

Human papillomavirus-related oropharyngeal squamous cell carcinoma (HPV+ OPSCC) represents a unique disease entity within head and neck cancer with rising incidence. Previous work has shown that alternative splicing events (ASEs) are prevalent in HPV+ OPSCC, but further validation is needed to under...

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Bibliographic Details
Main Authors: Theresa Guo, Kristina Diana A. Zambo, Fernando T. Zamuner, Tingting Ou, Christopher Hopkins, Dylan Z. Kelley, Hildegard A. Wulf, Eli Winkler, Rossin Erbe, Ludmila Danilova, Michael Considine, David Sidransky, Alexander Favorov, Liliana Florea, Elana J. Fertig, Daria A. Gaykalova
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Epigenetics
Subjects:
human papillomavirus
oropharyngeal cancer
alternative splicing
super-enhancers
Online Access:http://dx.doi.org/10.1080/15592294.2020.1741757

Internet

http://dx.doi.org/10.1080/15592294.2020.1741757

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