Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells.

Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells.

BACKGROUND: Colorectal cancer (CRC) has the third highest mortality rates among the US population. According to the most recent concept of carcinogenesis, human tumors are organized hierarchically, and the top of it is occupied by malignant stem cells (cancer stem cells, CSCs, or cancer-initiating c...

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Main Authors: Rebecca A Rowehl, Stephanie Burke, Agnieszka B Bialkowska, Donald W Pettet, Leahana Rowehl, Ellen Li, Eric Antoniou, Yuanhao Zhang, Roberto Bergamaschi, Kenneth R Shroyer, Iwao Ojima, Galina I Botchkina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4055451?pdf=render

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http://europepmc.org/articles/PMC4055451?pdf=render

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