Poly(ethylene glycol)-sheddable reduction-sensitive polyurethane micelles for triggered intracellular drug delivery for osteosarcoma treatment

Background: The survival rate of osteosarcoma therapy still lags behind overall cancer therapies due to the intrinsic or acquired drug resistance. Developing novel drug delivery systems that may overcome drug resistance would greatly facilitate osteosarcoma therapy. Methods: Poly(ethylene glycol) (P...

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Bibliographic Details
Main Authors: Zhengjie Yang, Qianping Guo, Yan Cai, Xuesong Zhu, Caihong Zhu, Yuling Li, Bin Li
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Orthopaedic Translation
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X19302402