Single cell sequencing revealed the mechanism of PD-1 resistance affected by the expression profile of peripheral blood immune cells in ESCC

Single cell sequencing revealed the mechanism of PD-1 resistance affected by the expression profile of peripheral blood immune cells in ESCC

BackgroundEsophageal squamous carcinoma (ESCC) is a highly lethal malignancy with poor prognosis. The effect of transcriptome characteristics of patient immune microenvironment (TME) on the efficacy of immunosuppressive agents is still poorly understood.MethodsHere we extracted and isolated immune c...

Full description

Bibliographic Details
Main Authors: Ting Deng, Huiya Wang, Changliang Yang, Mengsi Zuo, Zhi Ji, Ming Bai, Tao Ning, Rui Liu, Junyi Wang, Shaohua Ge, Le Zhang, Yi Ba, Haiyang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
single cell sequencing
PD-1 mMAB
peripheral blood
immune cells
ESCC
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1004345/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1004345/full

Similar Items