Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1
Objective: The distal dying-back of the longest nerve fibres is a hallmark of diabetic neuropathy, and impaired provision of energy in the form of adenosine triphosphate (ATP) may contribute to this neurodegenerative process. We hypothesised that energy supplementation via glycolysis and/or mitochon...
Autori principali: | , , , , , |
---|---|
Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Elsevier
2021-07-01
|
Serie: | Molecular Metabolism |
Soggetti: | |
Accesso online: | http://www.sciencedirect.com/science/article/pii/S2212877821000314 |