TudS desulfidases recycle 4-thiouridine-5’-monophosphate at a catalytic [4Fe-4S] cluster

TudS desulfidases recycle 4-thiouridine-5’-monophosphate at a catalytic [4Fe-4S] cluster

Abstract In all domains of life, transfer RNAs (tRNAs) contain post-transcriptionally sulfur-modified nucleosides such as 2- and 4-thiouridine. We have previously reported that a recombinant [4Fe-4S] cluster-containing bacterial desulfidase (TudS) from an uncultured bacterium catalyzes the desulfura...

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Bibliographic Details
Main Authors: Jonathan Fuchs, Rapolas Jamontas, Maren Hellen Hoock, Jonathan Oltmanns, Béatrice Golinelli-Pimpaneau, Volker Schünemann, Antonio J. Pierik, Rolandas Meškys, Agota Aučynaitė, Matthias Boll
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05450-5

Internet

https://doi.org/10.1038/s42003-023-05450-5

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