A model for the study of skeletal anomalies in rat fetuses

The aim of this study was to validate a model of skeletal anomalies in rat fetuses by the administration of ketoconazole (80 mg/kg) to pregnant rats during organogenesis. Bones of the head, trunk and anterior and posterior limbs were examined for detection of anomalies. Statistical differences regar...

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Bibliographic Details
Main Authors: Cristiane Effting, Daniel Jesus de Paula, Guilhermino Pereira Nunes Junior
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2004-03-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132004000100005