Molecular screening for potential selective antagonists of TRPA<sub>1</sub> ion channel

Molecular screening for potential selective antagonists of TRPA<sub>1</sub> ion channel

The article discusses the results of analysis a number of candidate molecules for TRPA1 ion channel selective antagonists using molecular modeling methods of high throughput screening. The study determined their mechanisms of action and specific activity in cells with overexpression of TRPA1 ion cha...

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Bibliographic Details
Main Authors: E. A. Beskhmelnitsyna, D. V. Kravchenko, M. V. Pokrovsky, M. V. Korokin, A. A. Peresypkina, E. I. Varavin, D. A. Kostina
Format: Article
Language:Russian
Published: NEICON ISP LLC 2018-02-01
Series:Ведомости Научного центра экспертизы средств медицинского применения
Subjects:
ионный канал trpa<sub>1</sub>
боль
ноцицепция
воспаление
высокопроизводительный молекулярный скрининг
молекулы-кандидаты в селективные антагонисты ионного канала trpa<sub>1</sub>
trpa<sub>1 </sub>ion channel
pain
nociception
inflammation
high throughput screening
candidate molecules for selective antagonists of trpa<sub>1 </sub>ion channel
Online Access:https://www.vedomostincesmp.ru/jour/article/view/140

Internet

https://www.vedomostincesmp.ru/jour/article/view/140

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