Towards Antibacterial Agents: Synthesis and Biological Activity of Multivalent Amide Derivatives of Thiacalix[4]arene with Hydroxyl and Amine Groups

Towards Antibacterial Agents: Synthesis and Biological Activity of Multivalent Amide Derivatives of Thiacalix[4]arene with Hydroxyl and Amine Groups

Antimicrobial resistance to modern antibiotics stimulates the search for new ways to synthesize and modify antimicrobial drugs. The development of synthetic approaches that can easily change different fragments of the molecule is a promising solution to this problem. In this work, a synthetic approa...

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Bibliographic Details
Main Authors: Igor Shiabiev, Dmitry Pysin, Alan Akhmedov, Olga Babaeva, Vasily Babaev, Anna Lyubina, Alexandra Voloshina, Konstantin Petrov, Pavel Padnya, Ivan Stoikov
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
thiacalixarene
synthesis
antibacterial activity
Gram-positive bacteria
cytotoxicity
antibacterial agent
Online Access:https://www.mdpi.com/1999-4923/15/12/2731

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https://www.mdpi.com/1999-4923/15/12/2731

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