A New Evolutionary Machine Learning Approach for Identifying Pyrene Induced Hepatotoxicity and Renal Dysfunction in Rats

Pyrene, composed of four fused benzene rings, is a polycyclic aromatic hydrocarbon (PAH) that has served as a model compound for evaluating the toxic effects of PAHs. In this paper, 114 male rats were dosed daily by oral gavage with either vehicle (corn oil) or pyrene (1500 mg/kg/day) for four days....

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Bibliographic Details
Main Authors: Jiayin Zhu, Fengting Zhu, Siyi Huang, Gang Wang, Huiling Chen, Xuehua Zhao, Shu-Yun Zhang
Format: Article
Language:English
Published: IEEE 2019-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/8585035/