Antinociceptive and Cardiorespiratory Effects of a Single Dose of Dexmedetomidine in Laboratory Mice Subjected to Craniotomy under General Anaesthesia with Isoflurane and Carprofen or Meloxicam

Antinociceptive and Cardiorespiratory Effects of a Single Dose of Dexmedetomidine in Laboratory Mice Subjected to Craniotomy under General Anaesthesia with Isoflurane and Carprofen or Meloxicam

Pain refinement represents an important aspect of animal welfare in laboratory animals. Refining analgesia regimens in mice undergoing craniotomy has been sparsely investigated. Here, we sought to investigate the effect of dexmedetomidine in combination with other analgesic drugs on intraoperative a...

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Bibliographic Details
Main Authors: Anika R. Schiele, Inken S. Henze, Regula Bettschart-Wolfensberger, Thomas C. Gent
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Animals
Subjects:
mice
craniotomy
dexmedetomidine
analgesia
anti-nociception
anaesthesia
Online Access:https://www.mdpi.com/2076-2615/14/6/913

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https://www.mdpi.com/2076-2615/14/6/913

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