CSN6‐SPOP‐HMGCS1 Axis Promotes Hepatocellular Carcinoma Progression via YAP1 Activation

CSN6‐SPOP‐HMGCS1 Axis Promotes Hepatocellular Carcinoma Progression via YAP1 Activation

Abstract Cholesterol metabolism has important roles in maintaining membrane integrity and countering the development of diseases such as obesity and cancers. Cancer cells sustain cholesterol biogenesis for their proliferation and microenvironment reprograming even when sterols are abundant. However,...

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Bibliographic Details
Main Authors: Kai Li, Jiayu Zhang, Haiwen Lyu, Jinneng Yang, Wenxia Wei, Yuzhi Wang, Haidan Luo, Yijing Zhang, Xin Jiang, Hairong Yi, Mengan Wang, Caiyun Zhang, Kang Wu, Lishi Xiao, Weijie Wen, Hui Xu, Guolin Li, Yunle Wan, Fang Yang, Runxiang Yang, Xinhui Fu, Baifu Qin, Zhongguo Zhou, Haipeng Zhang, Mong‐Hong Lee
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
cholesterol metabolism
hepatocellular carcinoma(HCC)
HFD
YAP1
Online Access:https://doi.org/10.1002/advs.202306827

Internet

https://doi.org/10.1002/advs.202306827

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