Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients

Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients

Abstract Psoriasis vulgaris (PV) is an inflammatory skin disease largely driven by aberrant αβT cells. Mucosal-associated invariant T (MAIT) cells, which constitute the largest circulating innate-like αβT cell community in human adults, are characterized by a semi-invariant TCRVα7.2 receptor and MR1...

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Main Authors: Maja Jirouš Drulak, Zvonimir Grgić, Vera Plužarić, Marija Šola, Teuta Opačak-Bernardi, Barbara Viljetić, Kristina Glavaš, Maja Tolušić-Levak, Vlatka Periša, Martina Mihalj, Mario Štefanić, Stana Tokić
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48321-z

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https://doi.org/10.1038/s41598-023-48321-z

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