Germline and Somatic mutations in postmenopausal breast cancer patients

Germline and Somatic mutations in postmenopausal breast cancer patients

OBJECTIVES: In breast cancer (BC) patients, the frequency of germline BRCA mutations (gBRCA) may vary according to the ethnic background, age, and family history of cancer. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) is the second most common somatic mutated gene...

Full description

Bibliographic Details
Main Authors: Tauana Rodrigues Nagy, Simone Maistro, Giselly Encinas, Maria Lucia Hirata Katayama, Glaucia Fernanda de Lima Pereira, Nelson Gaburo-Júnior, Lucas Augusto Moyses Franco, Ana Carolina Ribeiro Chaves de Gouvêa, Maria del Pilar Estevez Diz, Luiz Antonio Senna Leite, Maria Aparecida Azevedo Koike Folgueira
Format: Article
Language:English
Published: Elsevier España 2021-07-01
Series:Clinics
Subjects:
Breast Cancer
Germline Mutation
Somatic Mutation
BRCA1
BRCA2
PIK3CA
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322021000100291&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322021000100291&tlng=en

Similar Items