Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels

Characterising the longevity of immunological memory requires establishing the rules underlying the renewal and death of peripheral T cells. However, we lack knowledge of the population structure and how self-renewal and de novo influx contribute to the maintenance of memory compartments. Here, we c...

Full description

Bibliographic Details
Main Authors: Graeme Gossel, Thea Hogan, Daniel Cownden, Benedict Seddon, Andrew J Yates
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/23013