Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels
Characterising the longevity of immunological memory requires establishing the rules underlying the renewal and death of peripheral T cells. However, we lack knowledge of the population structure and how self-renewal and de novo influx contribute to the maintenance of memory compartments. Here, we c...
Main Authors: | Graeme Gossel, Thea Hogan, Daniel Cownden, Benedict Seddon, Andrew J Yates |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/23013 |
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