AcaFinder: Genome Mining for Anti-CRISPR-Associated Genes

ABSTRACT Anti-CRISPR (Acr) proteins are encoded by (pro)viruses to inhibit their host’s CRISPR-Cas systems. Genes encoding Acr and Aca (Acr associated) proteins often colocalize to form acr-aca operons. Here, we present AcaFinder as the first Aca genome mining tool. AcaFinder can (i) predict Acas an...

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Bibliographic Details
Main Authors: Bowen Yang, Jinfang Zheng, Yanbin Yin
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msystems.00817-22