Transglutaminase Type 2-MITF axis regulates phenotype switching in skin cutaneous melanoma

Transglutaminase Type 2-MITF axis regulates phenotype switching in skin cutaneous melanoma

Abstract Skin cutaneous melanoma (SKCM) is the deadliest form of skin cancer due to its high heterogeneity that drives tumor aggressiveness. Melanoma plasticity consists of two distinct phenotypic states that co-exist in the tumor niche, the proliferative and the invasive, respectively associated wi...

Full description

Bibliographic Details
Main Authors: Silvia Muccioli, Valentina Brillo, Tatiana Varanita, Federica Rossin, Elisabetta Zaltron, Angelo Velle, Giorgia Alessio, Beatrice Angi, Filippo Severin, Anna Tosi, Manuela D’Eletto, Luca Occhigrossi, Laura Falasca, Vanessa Checchetto, Roberto Ciaccio, Amelia Fascì, Leonardo Chieregato, Ana Paula Rebelo, Marta Giacomello, Antonio Rosato, Ildikò Szabò, Chiara Romualdi, Mauro Piacentini, Luigi Leanza
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06223-y

Internet

https://doi.org/10.1038/s41419-023-06223-y

Similar Items