Activation of Invariant Natural Killer T Cells Redirects the Inflammatory Response in Neonatal Sepsis

Activation of Invariant Natural Killer T Cells Redirects the Inflammatory Response in Neonatal Sepsis

Sepsis is the third leading cause of death in the neonatal population, due to susceptibility to infection conferred by immaturity of both the innate and adaptive components of the immune system. Invariant natural killer T (iNKT) cells are specialized adaptive immune cells that possess important inna...

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Bibliographic Details
Main Authors: Alexandra C. Bolognese, Weng-Lang Yang, Laura W. Hansen, Archna Sharma, Jeffrey M. Nicastro, Gene F. Coppa, Ping Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
neonatal sepsis
invariant natural killer T cells
KRN7000
CD1d
inflammation
lung injury
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00833/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00833/full

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