Preliminary evaluations of 3-dimensional human skin models for their ability to facilitate in vitro the long-term development of the debilitating obligatory human parasite Onchocerca volvulus.

Onchocerciasis also known as river blindness is a neglected tropical disease and the world's second-leading infectious cause of blindness in humans; it is caused by Onchocerca volvulus. Current treatment with ivermectin targets microfilariae and transmission and does not kill the adult parasite...

Full description

Bibliographic Details
Main Authors: Christoph Malkmus, Shabnam Jawahar, Nancy Tricoche, Sara Lustigman, Jan Hansmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008503