Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling

Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling

Calcium ions (Ca2+) are essential for many cellular signaling mechanisms and enter the cytosol mostly through voltage-gated calcium channels. Here, using high-speed Ca2+ imaging up to 20 kHz in the rat layer five pyramidal neuron axon we found that activity-dependent intracellular calcium concentrat...

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Bibliographic Details
Main Authors: Naomi AK Hanemaaijer, Marko A Popovic, Xante Wilders, Sara Grasman, Oriol Pavón Arocas, Maarten HP Kole
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
axon initial segment
sodium channel
calcium imaging
node of Ranvier
Online Access:https://elifesciences.org/articles/54566

Internet

https://elifesciences.org/articles/54566

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