Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation

Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation

An extensive RNA binding protein atlas (RBPome) for primary T cells would be a useful resource. Here the authors use two different methods to characterise the mouse and human T cell RBPome and show regulation of Roquin-1/2 dependent and independent pathways.

Bibliographic Details
Main Authors: Kai P. Hoefig, Alexander Reim, Christian Gallus, Elaine H. Wong, Gesine Behrens, Christine Conrad, Meng Xu, Lisa Kifinger, Taku Ito-Kureha, Kyra A. Y. Defourny, Arie Geerlof, Josef Mautner, Stefanie M. Hauck, Dirk Baumjohann, Regina Feederle, Matthias Mann, Michael Wierer, Elke Glasmacher, Vigo Heissmeyer
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25345-5

Internet

https://doi.org/10.1038/s41467-021-25345-5

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