IL-12p40 deletion aggravates lipopolysaccharide-induced cardiac dysfunction in mice

IL-12p40 deletion aggravates lipopolysaccharide-induced cardiac dysfunction in mice

BackgroundCardiac dysfunction is one of the most common complications of sepsis and is associated with the adverse outcomes and high mortality of sepsis patients. IL-12p40, the common subunit of IL-12 and IL-23, has been shown to be involved in a variety of inflammation-related diseases, such as pso...

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Bibliographic Details
Main Authors: Menglin Liu, Zhen Wang, Jishou Zhang, Di Ye, Menglong Wang, Yao Xu, Mengmeng Zhao, Yongqi Feng, Xiyi Lu, Heng Pan, Wei Pan, Cheng Wei, Dan Tian, Wenqiang Li, Jingjun Lyu, Jing Ye, Jun Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
sepsis
IL-12p40 deletion
cardiac dysfunction
monocytes
LPS
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.950029/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.950029/full

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