Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo.

Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo.

Among human RNA viruses, hepatitis C virus (HCV) is unusual in that it causes persistent infection in the majority of infected people. To establish persistence, HCV evades host innate and adaptive immune responses by multiple mechanisms. Recent studies identified virus genome-derived small RNAs (vsR...

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Bibliographic Details
Main Authors: Nirjal Bhattarai, James H McLinden, Jinhua Xiang, M Meleah Mathahs, Warren N Schmidt, Thomas M Kaufman, Jack T Stapleton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006232

Internet

https://doi.org/10.1371/journal.ppat.1006232

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