Analytical study of RUNX1-RUNXT1, PML-RARA, CBFB-MYH11, BCR-ABL1p210, and KMT2-MLLT3 in Mexican children with acute myeloid leukemia: A multicenter study of the Mexican interinstitutional group for the identification of the causes of childhood leukemia (MIGICCL)

Analytical study of RUNX1-RUNXT1, PML-RARA, CBFB-MYH11, BCR-ABL1p210, and KMT2-MLLT3 in Mexican children with acute myeloid leukemia: A multicenter study of the Mexican interinstitutional group for the identification of the causes of childhood leukemia (MIGICCL)

BackgroundThe distribution of RUNX1-RUNXT1, PML-RARA, CBFB-MYH11, BCR-ABL1p210, and KMT2A-MLLT3 in the pediatric population with acute myeloid leukemia (AML) in many countries of Latin America is largely unknown. Therefore, we aimed to investigate the frequency of these fusion genes in children with...

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Main Authors: Omar Sepúlveda-Robles, Elva Jiménez-Hernández, Victoria Domínguez-Catzín, Eber Gómez-Flores, Jorge Alfonso Martín-Trejo, Janet Flores-Lujano, José Refugio Torres-Nava, Juan Carlos Núñez-Enríquez, Marlon De Ita, Aurora Medina-Sanson, Minerva Mata-Rocha, Blanca Angelica Morales-Castillo, Juan Carlos Bravata-Alcántara, Alan Steve Nájera-Cortés, Norberto Sánchez-Escobar, José Gabriel Peñaloza-Gonzalez, Rosa Martha Espinosa-Elizondo, Luz Victoria Flores-Villegas, Raquel Amador-Sanchez, Darío Orozco-Ruiz, Maria Luisa Pérez-Saldívar, Martha Margarita Velázquez-Aviña, Laura Elizabeth Merino-Pasaye, Karina Anastacia Solís-Labastida, Ana Itamar González-Ávila, Jessica Denisse Santillán-Juárez, Vilma Carolina Bekker-Méndez, Silvia Jiménez-Morales, Angélica Rangel-López, Haydeé Rosas-Vargas, Juan Manuel Mejía-Aranguré
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pediatrics
Subjects:
AML – acute myeloid leukaemia
fusion genes
translocation
pediatric population
Mexican population
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.946690/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2022.946690/full

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