Pitavastatin induces autophagy-dependent ferroptosis in MDA-MB-231 cells via the mevalonate pathway

Pitavastatin induces autophagy-dependent ferroptosis in MDA-MB-231 cells via the mevalonate pathway

Triple-negative breast cancer (TNBC) is more prone to recurrence and metastasis relative to other subtypes of breast cancer, leading to an extremely poor prognosis. The increasing potential chemoresistance of TNBC patients is mainly due to that tumor cells escape from apoptosis. In recent years, sta...

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Bibliographic Details
Main Authors: Wen-Juan Tang, Di Xu, Ming-Xing Liang, Guan-Qun Wo, Wen-Quan Chen, Jin-Hai Tang, Wei Zhang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Triple-negative breast cancer
Statin
Ferroptosis
Mevalonate pathway
Anticancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024031153

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024031153

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