Single-Nucleotide Polymorphisms in Base-Excision Repair-Related Genes Involved in the Risk of an Occurrence of Non-Alcoholic Fatty Liver Disease

Single-Nucleotide Polymorphisms in Base-Excision Repair-Related Genes Involved in the Risk of an Occurrence of Non-Alcoholic Fatty Liver Disease

Oxidative stress is one of the pillars crucial in the development of a non-alcoholic fatty liver disease (NAFLD) and may cause DNA damage. Since the main pathway responsible for the repair of oxidative DNA damage is the base-excision repair (BER) pathway, we examined the relationship between the pre...

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Bibliographic Details
Main Authors: Sylwia Ziółkowska, Marcin Kosmalski, Łukasz Kołodziej, Aleksandra Jabłkowska, Janusz Zbigniew Szemraj, Tadeusz Pietras, Maciej Jabłkowski, Piotr Lech Czarny
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
non-alcoholic fatty liver disease
metabolic fatty liver disease
insulin resistance
single-nucleotide polymorphism
base-excision repair
DNA repair
Online Access:https://www.mdpi.com/1422-0067/24/14/11307

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https://www.mdpi.com/1422-0067/24/14/11307

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