Cortactin-dependent control of Par1b-regulated epithelial cell polarity in Helicobacter infection
Cell polarity is crucial for gastric mucosal barrier integrity and mainly regulated by polarity-regulating kinase partitioning-defective 1b (Par1b). During infection, the carcinogen Helicobacter pylori hijacks Par1b via the bacterial oncoprotein CagA leading to loss of cell polarity, but the precise...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-06-01
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Series: | Cell Insight |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772892724000166 |