Targeting Glioblastoma via Selective Alteration of Mitochondrial Redox State

Targeting Glioblastoma via Selective Alteration of Mitochondrial Redox State

Glioblastoma is one of the most aggressive brain tumors, characterized by a pronounced redox imbalance, expressed in a high oxidative capacity of cancer cells due to their elevated glycolytic and mitochondrial oxidative metabolism. The assessment and modulation of the redox state of glioblastoma are...

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Bibliographic Details
Main Authors: Akira Sumiyoshi, Sayaka Shibata, Zhivko Zhelev, Thomas Miller, Dessislava Lazarova, Ichio Aoki, Takayuki Obata, Tatsuya Higashi, Rumiana Bakalova
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
glioblastoma
redox targeting
mitochondrial redox cycling
tumor-associated ENOX2
TGF-β1
menadione
Online Access:https://www.mdpi.com/2072-6694/14/3/485

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https://www.mdpi.com/2072-6694/14/3/485

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