Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
Abstract Background The major histocompatibility complex class I (MHC-I) molecule is a protein complex that displays intracellular peptides to T cells, allowing the immune system to recognize and destroy infected or cancerous cells. MHC-I is composed of a highly polymorphic HLA-encoded alpha chain t...
| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Makale |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
BMC
2019-07-01
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| Seri Bilgileri: | BMC Medical Genomics |
| Online Erişim: | http://link.springer.com/article/10.1186/s12920-019-0544-1 |