Single dose recombinant VSV based vaccine elicits robust and durable neutralizing antibody against Hantaan virus

Single dose recombinant VSV based vaccine elicits robust and durable neutralizing antibody against Hantaan virus

Abstract Hantaan virus (HTNV) is a pathogenic orthohantavirus prevalent in East Asia that is known to cause hemorrhagic fever with severe renal syndrome (HFRS), which has a high fatality rate. However, a Food and Drug Administration (FDA)-approved vaccine is not currently available against this viru...

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Bibliographic Details
Main Authors: Hui Zhang, He Liu, Jing Wei, Yamei Dang, Yuan Wang, Qiqi Yang, Liang Zhang, Chuantao Ye, Bin Wang, Xiaolei Jin, Linfeng Cheng, Hongwei Ma, Yangchao Dong, Yinghui Li, Yinlan Bai, Xin Lv, Yingfeng Lei, Zhikai Xu, Wei Ye, Fanglin Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00814-2

Internet

https://doi.org/10.1038/s41541-024-00814-2

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