Losartan Prevents Maladaptive Auditory-Somatosensory Plasticity After Hearing Loss via Transforming Growth Factor-β Signaling Suppression

Losartan Prevents Maladaptive Auditory-Somatosensory Plasticity After Hearing Loss via Transforming Growth Factor-β Signaling Suppression

Objectives Hearing loss disrupts the balance of auditory-somatosensory inputs in the cochlear nucleus (CN) of the brainstem, which has been suggested to be a mechanism of tinnitus. This disruption results from maladaptive auditory-somatosensory plasticity, which is a form of axonal sprouting. Axonal...

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Bibliographic Details
Main Authors: Seog-Kyun Mun, Kyu-Hee Han, Jong Tae Baek, Suk-Won Ahn, Hyun Sang Cho, Mun Young Chang
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2019-02-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Hearing Loss
Auditory-Somatosensory Plasticity
Tinnitus
Losartan
Online Access:http://www.e-ceo.org/upload/pdf/ceo-2018-00542.pdf

Internet

http://www.e-ceo.org/upload/pdf/ceo-2018-00542.pdf

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