Multiple Isocyanide insertions promoted by protic and Lewis acids

The protonation, or Lewis Acid complexation, of electrophiles can trigger the sequential insertion of two or more isocyanides resulting in valuable iminonitriles or heterocycles. The number of insertions is controlled by the nature of the alkyl- or arylisocyanide and by the presence of a proximal nu...

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Bibliographic Details
Main Authors: John Kornfeind, Fraser F. Fleming
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Tetrahedron Chem
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666951X23000220