Characterization of Lung Injury following Abrin Pulmonary Intoxication in Mice: Comparison to Ricin Poisoning

Characterization of Lung Injury following Abrin Pulmonary Intoxication in Mice: Comparison to Ricin Poisoning

Abrin is a highly toxic protein obtained from the seeds of the rosary pea plant <i>Abrus precatorius</i>, and it is closely related to ricin in terms of its structure and chemical properties. Both toxins inhibit ribosomal function, halt protein synthesis and lead to cellular death. The m...

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Bibliographic Details
Main Authors: Anita Sapoznikov, Yoav Gal, Ron Alcalay, Yentl Evgy, Tamar Sabo, Chanoch Kronman, Reut Falach
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Toxins
Subjects:
abrin
ricin
intranasal
lungs
alveolar epithelial type II cells
neutrophils
Online Access:https://www.mdpi.com/2072-6651/14/9/614

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https://www.mdpi.com/2072-6651/14/9/614

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