Targeting the ATP synthase in bacterial and fungal pathogens: beyond Mycobacterium tuberculosis

Targeting the ATP synthase in bacterial and fungal pathogens: beyond Mycobacterium tuberculosis

ABSTRACT: The ATP synthase is a multicomponent enzyme that is largely conserved across the kingdoms of life. In many species the ATP synthase is central in the synthesis of ATP by using the electrochemical proton gradient generated via the electron transport chain. Bacteria inhabit very diverse ecol...

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Bibliographic Details
Main Authors: Martin Vestergaard, Dirk Bald, Hanne Ingmer
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
ATP synthase
Metabolism
Inhibitors
Membrane polarization
Antibiotic adjuvant target
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716522000303

Internet

http://www.sciencedirect.com/science/article/pii/S2213716522000303

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