Oxidative stress tolerance contributes to heterologous protein production in Pichia pastoris

Abstract Background Pichia pastoris (syn. Komagataella phaffii) is an important yeast system for heterologous protein expression. A robust P. pastoris mutant with oxidative and thermal stress cross-tolerance was acquired in our previous study. The robust mutant can express a 2.5-fold higher level of...

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Bibliographic Details
Main Authors: Nai-Xin Lin, Rui-Zhen He, Yan Xu, Xiao-Wei Yu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Biotechnology for Biofuels
Subjects:
Online Access:https://doi.org/10.1186/s13068-021-02013-w