Production and immunogenicity of a deoxyribonucleic acid Alphavirus vaccine expressing classical swine fever virus E2-Erns protein and porcine Circovirus Cap-Rep protein

Production and immunogenicity of a deoxyribonucleic acid Alphavirus vaccine expressing classical swine fever virus E2-Erns protein and porcine Circovirus Cap-Rep protein

Classical swine fever virus (CSFV) and porcine Circovirus type 2 (PCV2) are economically pivotal infectious disease viruses of swine. Alphaviral RNA replicon plasmids have been used as an important vector for constructing nucleic acid vaccines. Here, we aimed to construct a recombinant alphaviral pl...

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Bibliographic Details
Main Authors: Fuyu Du, Zhi Cao, Zixuan Ye, Jun He, Weijie Zhang, Ke Zhang, Pengbo Ning
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
DNA bivalent vaccine
CSFV
PCV2
coinfection
alphaviral plasmid
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1065532/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1065532/full

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