Saquayamycin B<sub>1</sub> Suppresses Proliferation, Invasion, and Migration by Inhibiting PI3K/AKT Signaling Pathway in Human Colorectal Cancer Cells

Saquayamycin B<sub>1</sub> Suppresses Proliferation, Invasion, and Migration by Inhibiting PI3K/AKT Signaling Pathway in Human Colorectal Cancer Cells

Moromycin B (Mor B), saquayamycin B<sub>1</sub> (Saq B<sub>1</sub>), saquayamycin B (Saq B), and landomycin N (Lan N), four angucyclines produced by the marine-derived actinomycete <i>Streptomyces</i> sp., are a class of polyketone compounds containing benzanthrac...

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Bibliographic Details
Main Authors: Jianjiang Li, Ningning Han, Hao Zhang, Xiaoyu Xie, Yaoyao Zhu, E Zhang, Jiahui Ma, Chuangeng Shang, Mengxiong Yin, Weidong Xie, Xia Li
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Marine Drugs
Subjects:
saquayamycin B<sub>1</sub>
colorectal cancer
PI3K/AKT
EMT
apoptosis
structure–activity relationship
Online Access:https://www.mdpi.com/1660-3397/20/9/570

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https://www.mdpi.com/1660-3397/20/9/570

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