Morphological analysis of Apolipoprotein E binding to Aβ Amyloid using a combination of Surface Plasmon Resonance, Immunogold Labeling and Scanning Electron Microscopy

Morphological analysis of Apolipoprotein E binding to Aβ Amyloid using a combination of Surface Plasmon Resonance, Immunogold Labeling and Scanning Electron Microscopy

Abstract Background Immunogold labeling in combination with transmission electron microscopy analysis is a technique frequently used to correlate high-resolution morphology studies with detailed information regarding localization of specific antigens. Although powerful, the methodology has limitatio...

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Bibliographic Details
Main Authors: Tohidul Islam, Anna L. Gharibyan, Cheng Choo Lee, Anders Olofsson
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Biotechnology
Subjects:
Aβ
ApoE
Immunogold
Surface plasmon resonance
SPR
Scanning electron microscopy
Online Access:https://doi.org/10.1186/s12896-019-0589-4

Internet

https://doi.org/10.1186/s12896-019-0589-4

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