Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour.

The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement. We recently proposed an alternative mechanism, supported by several...

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Bibliographic Details
Main Authors: Matthew P Neilson, Douwe M Veltman, Peter J M van Haastert, Steven D Webb, John A Mackenzie, Robert H Insall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3096608?pdf=render