Non-enzymatic formation of isoprene and 2-methyl-3-buten-2-ol (2-MBO) by manganese

Abstract It has been suggested that isoprene synthesis by isoprene synthase (IspS) proceeds via a substrate-assisted mechanism. The authors observed a non-enzymatic isoprene formation by Mn2+, which represents the basis of IspS enzyme reaction. Because IspS and many other terpene synthases require M...

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Bibliographic Details
Main Authors: Hirosuke Oku, Ishmael Mutanda, Masakazu Fukuta, Masashi Inafuku
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-06520-0